I'm choosing column 4 for several strategic reasons: 
1. This extends my horizontal line to three consecutive pieces (in columns 2, 3, and 4)
2. It blocks my opponent's potential horizontal expansion to the left
3. It maintains control near the center of the board, which provides more winning opportunities
4. While this places my piece above an opponent's X (allowing them to play in column 4 next), the benefits of blocking their horizontal line and extending my own outweigh this disadvantage
5. This move creates potential for multiple winning threats in future turns