I'm choosing column 2 (adjacent to my opponent's piece) for a few reasons: 
1. It maintains control of the center area of the board
2. By playing adjacent to my opponent's piece, I prevent them from easily building a horizontal sequence
3. This position gives me flexibility for future moves in multiple directions
4. It doesn't create any immediate advantages for my opponent
5. Column 2 allows me potential diagonal and horizontal connection opportunities as the game progresses