I should place my O at the bottom-left position (2,0) to create a diagonal threat. This gives me two potential winning paths:
1. The diagonal from bottom-left (2,0) through center to top-right would be blocked by opponent's X at center.
2. But more importantly, this creates a strong vertical threat in the left column from (0,0) to (2,0).

After this move, I'll have two Os in the left column, forcing the opponent to block at (1,0) in their next turn. This is strategically sound as it takes control of a corner which generally provides more winning opportunities in Tic-Tac-Toe. If the opponent doesn't block the left column, I can win on my next move.