I analyzed each possible move and found that playing at 2,1 creates a fork: placing an 'X' there forms two winning threats. In row 2, we would have X's at 2,1 and 2,2 with a win possible by playing at 2,0, and in column 1 we would have X's at 1,1 and 2,1 with a win possible by playing at 0,1. This forces the opponent to block only one threat, allowing me to win on my next turn. Therefore, move 2,1 is the best move.