Looking at the current board, I can see that playing at position 2,1 (bottom middle) creates the strongest strategic threat.

By placing my X at 2,1:
1. I establish a threat in the middle column, where I'll have Xs at positions (1,1) and (2,1)
2. This forces my opponent to respond to this threat by playing at 0,1 in their next move

What makes this move particularly strong is that it creates a potential winning scenario. If my opponent doesn't block my middle column threat by playing at 0,1, and instead plays at 0,2, I can win on my next move by playing at 0,1 - completing three Xs in the middle column.

Even if my opponent plays optimally by blocking at 0,1, the game will likely end in a draw, which is the best possible outcome when both players make optimal moves in Tic-Tac-Toe. Therefore, playing at 2,1 gives me the best chance to win while ensuring I don't lose.